Dermatitis is a common skin condition characterized by inflammation of the skin. The signs and symptoms of dermatitis include skin rashes, itching, and the formation of blisters and pustules. If the causes of dermatitis are not controlled properly, patients may also develop oozing of purulent discharge from the lesions and crusting and scarring of the skin. The various types of dermatitis includes atopic dermatitis, contact dermatitis, occupational dermatitis, dyshidrotic eczema, nummular eczema and seborrheic dermatitis. The diagnosis of the specific type of dermatitis is made based on the location of skin lesions, the characteristic symptoms and the underlying factors responsible for triggering the symptoms. In most cases, dermatitis occurs due to the exposure of skin to allergens or irritants such as soaps, detergents, perfumes, jewelry, and so on. However, an improperly functioning immune system is one of the common factors that trigger these causes of dermatitis. In fact, immune system dysfunctions have been found to be responsible for the higher risk of several skin diseases including psoriasis and eczema, as well. Let’s continue with the series of articles describing the role of the immune system in the development of dermatitis.

What are the immunological causes of dermatitis?

The hypersensitive response of immune cells

The incidence of allergic contact dermatitis has been found to be higher in patients having abnormal immune system functions. The symptoms of allergic contact dermatitis include a localized skin rash, itching, and swelling. These symptoms are triggered when a part of the skin comes in a direct contact with an allergen and irritant such as jewelry, detergents or environmental pollutants. It triggers a cell-mediated hypersensitivity reaction by the immune system. The reaction occurs due to the abnormal response of immune cells such as the T-cells including CD4+ and CD8+ T-cells. These causes of dermatitis can be managed effectively by regulating the response of these immune cells.

Triggers inflammation

It has been found that the dysfunctions related to the innate and adaptive immune systems are responsible for contributing to the causes of dermatitis. The symptoms of occupational dermatitis, contact dermatitis, and seborrheic dermatitis are characterized by inflammation of the skin. The direct contact or exposure of skin to metal ions at the workplace or chemicals in routinely used household items triggers an abnormal response of the innate and adaptive immune system. This results in the release of pro-inflammatory substances due to which patients experience skin rashes, itching, and redness. Controlling the release of these inflammatory substances and preventing the abnormal immune system reaction can be beneficial for controlling these causes of dermatitis.

Autoimmune response

In some cases, the immune system of the patients fails to identify the skin cells as the body’s own tissue and attacks them, resulting in their destruction. This condition is called autoimmune dermatitis. It is responsible for causing the symptoms of atopic dermatitis and seborrheic dermatitis. The self-destructive reaction of the immune system results in the release of cytokines, which further worsen the symptoms of dermatitis. It can cause long-term damage to the skin and even increase the risk of skin cancer. Thus, improperly managed dermatitis can lead to more serious complications. Also, the autoimmune reaction can also increase the risk of other skin diseases such as psoriasis. Hence, it is important to manage the immunological causes of dermatitis and control the symptoms of this disease. Dermatitis can be controlled effectively by using BioPro-Plus. This supplement is carefully formulated to regulate the functions of the immune system. It can control the production of T-cells thus providing relief from the symptoms caused due to skin inflammation. BioPro-Plus can also regulate the response of the immune cells to allergens, irritants as well as the body’s own cells thus helping to prevent allergic dermatitis, occupational dermatitis and autoimmune dermatitis. This helps to control the common immunologically-linked causes of dermatitis. This supplement can also help provide protection against skin infections by strengthening immune functions. Hence, patients are advised to use BioPro-Plus on a regular basis to derive relief from the symptoms and prevent complications of this disease.

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